Tamoxifen: An Investigative Review for Nano Dosage Forms and Hyphenated Techniques

Tamoxifen (TAM), a non-steroidal antiestrogen, has revolutionized female breast cancer treatment. The mechanism involves is to compete with 17β-estradiol (E2) at the receptor site and blocking promotional role of E2 in cancer. Tam pioneering medicine because its widespread usage treatment chemoprevention, as well research into novel selective estrogen modulators (SERMs). In vast majority patients, TAM cost-effective, life-saving, free significant adverse effects. this context, review presents several nanoformulations for selectively delivered lower dosages tumors. Various TAM-containing nanosystems have been effectively created deliver particular molecular targets decreasing harmful Following that, there summary chromatographic techniques quantify drug human biological samples. quantification different matrices major importance assist control quality, efficacy, safety.